Cov neeg feem coob paub txog Parkinson's thiab Alzheimer's.Parkinson tus kab mob yog ib hom kab mob neurodegenerative.Nws muaj ntau dua nyob rau hauv cov neeg laus.Lub hnub nyoog nruab nrab ntawm qhov pib yog nyob ib ncig ntawm 60 xyoo.Cov tub ntxhais hluas uas muaj tus kab mob Parkinson muaj hnub nyoog qis dua 40 xyoo tsis tshua muaj.Feem ntau ntawm PD ntawm cov neeg muaj hnub nyoog 65 xyoos hauv Suav teb yog kwv yees li 1.7%.Feem ntau cov neeg mob uas muaj tus kab mob Parkinson yog ib qho mob me me, thiab tsawg dua 10% ntawm cov neeg mob muaj keeb kwm hauv tsev neeg.Qhov tseem ceeb tshaj plaws kev hloov pauv pathological hauv Parkinson tus kab mob yog degeneration thiab tuag ntawm dopaminergic neurons nyob rau hauv substantia nigra ntawm lub midbrain.Qhov tseeb ntawm qhov kev hloov pauv pathological no tseem tsis tau paub meej.Cov yam ntxwv ntawm caj ces, ib puag ncig yam, kev laus, thiab kev ntxhov siab oxidative tej zaum yuav cuam tshuam rau kev degeneration thiab tuag ntawm PH dopaminergic neurons.Nws cov tsos mob tshwm sim feem ntau suav nrog kev pw tsaug zog, bradykinesia, myotonia thiab postural gait cuam tshuam, thaum cov neeg mob tuaj yeem nrog cov tsos mob tsis yog lub cev muaj zog xws li kev nyuaj siab, cem quav thiab pw tsaug zog.
Dementia, tseem hu ua Alzheimer's kab mob, yog ib qho mob neurodegenerative uas muaj qhov tshwm sim tsis zoo.Clinically, nws yog tus cwj pwm los ntawm kev dementia dav dav, xws li kev tsis nco qab, aphasia, apraxia, agnosia, kev puas tsuaj ntawm cov kev txawj visuospatial, kev ua haujlwm tsis zoo, thiab kev hloov ntawm tus cwj pwm thiab tus cwj pwm.Cov uas pib ua ntej hnub nyoog 65 xyoos yog hu ua Alzheimer's disease;cov neeg uas muaj pib tom qab hnub nyoog 65 xyoos yog hu ua Alzheimer's.
Ob yam kab mob no feem ntau ua rau cov neeg laus thiab ua rau menyuam yaus txhawj xeeb heev.Yog li ntawd, yuav ua li cas los tiv thaiv qhov tshwm sim ntawm ob kab mob no ib txwm yog ib qho kev tshawb fawb hotspot ntawm kws tshawb fawb.Tuam Tshoj yog lub teb chaws loj rau kev tsim tshuaj yej thiab haus tshuaj yej.Ntxiv nrog rau kev tshem cov roj thiab txo cov roj, tshuaj yej muaj qhov txiaj ntsig tsis txaus ntseeg, uas yog, nws tuaj yeem tiv thaiv Parkinson tus kab mob thiab Alzheimer's kab mob.
Cov tshuaj yej ntsuab muaj cov khoom xyaw tseem ceeb heev: epigallocatechin gallate, uas yog cov khoom muaj txiaj ntsig zoo tshaj plaws hauv tshuaj yej polyphenols thiab belongs rau catechins.
Ntau cov kev tshawb fawb tau pom tias epigallocatechin gallate tiv thaiv cov hlab ntsha los ntawm kev puas tsuaj hauv cov kab mob neurodegenerative.Cov kev tshawb fawb txog kev kis mob niaj hnub no tau pom tias haus tshuaj yej tsis zoo cuam tshuam nrog qhov tshwm sim ntawm qee cov kab mob neurodegenerative, yog li nws tau xav tias haus tshuaj yej tuaj yeem ua rau qee qhov kev tiv thaiv endogenous hauv cov hlwb neuronal.EGCG kuj muaj cov nyhuv antidepressant, thiab nws cov tshuaj tiv thaiv kev ntxhov siab feem ntau yog cuam tshuam nrog kev cuam tshuam ntawm γ-aminobutyric acid receptors.Rau cov neeg muaj tus kab mob HIV, tus kab mob-induced neurodementia yog ib txoj kev pathogenic, thiab cov kev tshawb fawb tsis ntev los no tau pom tias EGCG tuaj yeem thaiv cov txheej txheem pathological no.
EGCG feem ntau pom muaj nyob rau hauv cov tshuaj yej ntsuab, tab sis tsis nyob rau hauv cov tshuaj yej dub, yog li ib khob ntawm ntshiab tshuaj yej tom qab noj mov yuav tshem tau roj thiab txo greasy, uas yog heev noj qab nyob zoo.EGCE muab rho tawm los ntawm cov tshuaj yej ntsuab tuaj yeem siv rau hauv cov khoom noj qab haus huv thiab kev noj haus, thiab nws yog ib qho cuab yeej zoo los tiv thaiv cov kab mob saum toj no.
Post lub sij hawm: Apr-06-2022
